1 Result for "

2489446-59-3

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "2489446-59-3" in MCE Product Catalog:

Cat. No.: HY-144710
CAS No.: 2489446-59-3
Target:  

FLT3

Research Areas:  

Cancer

FLT3/ITD-IN-2 (Compound 17) is a potent FLT3 internal tandem duplications (FLT3-ITD) inhibitor with IC50 values of 0.3, 0.4 and 1.0 nM against FLT3 D835Y, FLT3 and FLT3-ITD, respectively. FLT3/ITD-IN-2 potently inhibits the phosphorylation of FLT3 and displays excellent antiproliferative activities against acute myeloid leukemia cell lines .
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