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FLT3/ITD-IN-2

FLT3/ITD-IN-2 (Compound 17) is a potent FLT3 internal tandem duplications (FLT3-ITD) inhibitor with IC50 values of 0.3, 0.4 and 1.0 nM against FLT3D835Y, FLT3 and FLT3-ITD, respectively. FLT3/ITD-IN-2 potently inhibits the phosphorylation of FLT3 and displays excellent antiproliferative activities against acute myeloid leukemia cell lines.

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  • CAS No.: 2489446-59-3
  • Formula: C23H26F3N7O2
  • Molecular Weight:489.49
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • FLT3/ITD-IN-2 Chemical Structure
    FLT3/ITD-IN-2 Chemical Structure
CAS No.: 2489446-59-3
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  • FLT3/ITD-IN-2 Chemical Structure
    FLT3/ITD-IN-2 Chemical Structure
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  • FLT3/ITD-IN-2