1 Result for "

2DG-ODDA

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "2DG-ODDA" in MCE Product Catalog:

Cat. No.: HY-179631
Target:  

Apoptosis

Research Areas:  

Cancer

2DG-ODDA is a 2-deoxyglucose (2-DG) (HY-13966) derivative with potent antitumor activity. 2DG-ODDA induces apoptosis, and reduces ATP production. 2DG-ODDA is taken up through both fatty acid and glucose transporters and is cleaved by α-Mannosidase (HY-P2950), releases 2DG to inhibit N-glycosylation and disrupt cellular metabolism. 2DG-ODDA inhibits tumor growth in a 4T1 mouse model. 2DG-ODDA can be used for the research of triple-negative breast cancer (TNBC) .
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