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3-Methoxybenzaldehyde

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Amino Acid Derivatives (1) Bacterial (1) Endogenous Metabolite (4) Fungal (1) IRE1 (2) Isotope-Labeled Compounds (1) Prolyl Endopeptidase (PREP) (1) Reference Standards (2)
By Research Areas:	Cancer (2) Infection (1) Inflammation/Immunology (5) Neurological Disease (1)
Click Chemistry:	Alkynes (1)

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Isotope-Labeled Compounds

Click Chemistry

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-W007346

m-Anisaldehyde 3-Methoxybenzaldehyde	Endogenous Metabolite	Inflammation/Immunology
m-Anisaldehyde (3-Methoxybenzaldehyde) is an endogenous metabolite. 3-Methoxybenzaldehyde is associated with thyroid autoimmunity during early pregnancy .

HY-107371

6-Bromo-2-hydroxy-3-methoxybenzaldehyde NSC95682	IRE1	Inflammation/Immunology Cancer
6-Bromo-2-hydroxy-3-methoxybenzaldehyde (NSC95682) (Compound 3-5) is a selective and potent IRE-1α inhibitor with an IC₅₀ value of 0.08 μM. 6-Bromo-2-hydroxy-3-methoxybenzaldehyde can be used for research on diseases associated with the unfolded protein response (UPR), such as cancer and autoimmune diseases .

HY-W007346R

m-Anisaldehyde (Standard) 3-Methoxybenzaldehyde (Standard)	Reference Standards Endogenous Metabolite	Inflammation/Immunology
m-Anisaldehyde (Standard) is the analytical standard of m-Anisaldehyde (HY-W007346). This product is intended for research and analytical applications. m-Anisaldehyde (3-Methoxybenzaldehyde) is an endogenous metabolite. 3-Methoxybenzaldehyde is associated with thyroid autoimmunity during early pregnancy .

HY-151637

Fmoc-N-propargyl-MPBA	Amino Acid Derivatives	Others
Fmoc-N-propargyl-MPBA is a propargyl-substituted MPBA linker derived from 4-hydroxy-3-methoxybenzaldehyde. Fmoc-N-propargyl-MPBA can be elongated using standard Fmoc-based solid phase chemistry and linked to supports by standard coupling procedures . Fmoc-N-propargyl-MPBA is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

HY-P4308

*Z-Pro-Pro-aldehyde-dimethyl acetal*	Prolyl Endopeptidase (PREP)	Neurological Disease
Z-Pro-Pro-aldehyde-dimethyl acetal is a potent inhibitor of prolyl endopeptidase (PREP), a cytoplasmic serine endoprotease (IC₅₀= 12 nM). Z-Pro-Pro-aldehyde-dimethyl acetal plays an important role in cognitive dysfunction in aging and neurodegenerative diseases including Alzheimer's disease .

HY-W007346S

m-Anisaldehyde-d3	Endogenous Metabolite Isotope-Labeled Compounds	Inflammation/Immunology
m-Anisaldehyde-d₃ is the deuterium labeled m-Anisaldehyde (HY-W007346). m-Anisaldehyde (3-Methoxybenzaldehyde) is an endogenous metabolite. 3-Methoxybenzaldehyde is associated with thyroid autoimmunity during early pregnancy .

HY-77995S

*2-Methoxybenzaldehyde-d3* o-Anisaldehyde-d₃	Fungal Bacterial	Infection
2-Methoxybenzaldehyde-d₃ is the deuterium labeled 2-Methoxybenzaldehyde . 2-Methoxybenzaldehyde (o-Anisaldehyde), isolated from cinnamon essential oil (CEO), exists antibacterial and antifungal activity .

HY-Y0740S1

*4-Methoxybenzaldehyde-d3*	Endogenous Metabolite	Others
4-Methoxybenzaldehyde-d₃ is the deuterium labeled 4-Methoxybenzaldehyde . 4-Methoxybenzaldehyde is a naturally occurring fragrant phenolic compound. 4-Methoxybenzaldehyde has been found in many plant species including horseradish, anise, star anise. 4-Methoxybenzaldehyde is a possible neurotoxicant and it has shown effects that include mortality, attractancy, and interference with host seeking .

HY-107371R

*6-Bromo-2-hydroxy-3-methoxybenzaldehyde* (Standard)** NSC95682 (Standard)	Reference Standards IRE1	Inflammation/Immunology Cancer
6-Bromo-2-hydroxy-3-methoxybenzaldehyde (Standard) (NSC95682 (Standard)) is the analytical standard of 6-Bromo-2-hydroxy-3-methoxybenzaldehyde (HY-107371). This product is intended for research and analytical applications. 6-Bromo-2-hydroxy-3-methoxybenzaldehyde (NSC95682) (Compound 3-5) is a selective and potent IRE-1α inhibitor with an IC₅₀ value of 0.08 μM. 6-Bromo-2-hydroxy-3-methoxybenzaldehyde can be used for research on diseases associated with the unfolded protein response (UPR), such as cancer and autoimmune diseases .

*Z-Pro-Pro-aldehyde-dimethyl acetal*	Prolyl Endopeptidase (PREP)	Neurological Disease
Z-Pro-Pro-aldehyde-dimethyl acetal is a potent inhibitor of prolyl endopeptidase (PREP), a cytoplasmic serine endoprotease (IC₅₀= 12 nM). Z-Pro-Pro-aldehyde-dimethyl acetal plays an important role in cognitive dysfunction in aging and neurodegenerative diseases including Alzheimer's disease .

*Gly-Phe-Gly-Aldehyde* semicarbazone**	Peptides	Others
Gly-Phe-Gly-Aldehyde semicarbazone is a peptide.

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W007346

m-Anisaldehyde 3-Methoxybenzaldehyde	other families Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Plants Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
m-Anisaldehyde (3-Methoxybenzaldehyde) is an endogenous metabolite. 3-Methoxybenzaldehyde is associated with thyroid autoimmunity during early pregnancy .

HY-W007346R

m-Anisaldehyde (Standard) 3-Methoxybenzaldehyde (Standard)	Structural Classification Microorganisms other families Ketones, Aldehydes, Acids Plants Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
m-Anisaldehyde (Standard) is the analytical standard of m-Anisaldehyde (HY-W007346). This product is intended for research and analytical applications. m-Anisaldehyde (3-Methoxybenzaldehyde) is an endogenous metabolite. 3-Methoxybenzaldehyde is associated with thyroid autoimmunity during early pregnancy .

Cat. No.	Product Name	Chemical Structure

HY-W007346S

m-Anisaldehyde-d3
m-Anisaldehyde-d₃ is the deuterium labeled m-Anisaldehyde (HY-W007346). m-Anisaldehyde (3-Methoxybenzaldehyde) is an endogenous metabolite. 3-Methoxybenzaldehyde is associated with thyroid autoimmunity during early pregnancy .

HY-77995S

*2-Methoxybenzaldehyde-d3*
2-Methoxybenzaldehyde-d₃ is the deuterium labeled 2-Methoxybenzaldehyde . 2-Methoxybenzaldehyde (o-Anisaldehyde), isolated from cinnamon essential oil (CEO), exists antibacterial and antifungal activity .

HY-Y0740S1

*4-Methoxybenzaldehyde-d3*
4-Methoxybenzaldehyde-d₃ is the deuterium labeled 4-Methoxybenzaldehyde . 4-Methoxybenzaldehyde is a naturally occurring fragrant phenolic compound. 4-Methoxybenzaldehyde has been found in many plant species including horseradish, anise, star anise. 4-Methoxybenzaldehyde is a possible neurotoxicant and it has shown effects that include mortality, attractancy, and interference with host seeking .

4-Methoxybenzaldehyde-d3

4-Methoxybenzaldehyde-d₃ is the deuterium labeled 4-Methoxybenzaldehyde . 4-Methoxybenzaldehyde is a naturally occurring fragrant phenolic compound. 4-Methoxybenzaldehyde has been found in many plant species including horseradish, anise, star anise. 4-Methoxybenzaldehyde is a possible neurotoxicant and it has shown effects that include mortality, attractancy, and interference with host seeking .

Cat. No.	Product Name		Classification

HY-151637

Fmoc-N-propargyl-MPBA		Alkynes
Fmoc-N-propargyl-MPBA is a propargyl-substituted MPBA linker derived from 4-hydroxy-3-methoxybenzaldehyde. Fmoc-N-propargyl-MPBA can be elongated using standard Fmoc-based solid phase chemistry and linked to supports by standard coupling procedures . Fmoc-N-propargyl-MPBA is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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