3 Results for "

3-WP

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "3-WP" in MCE Product Catalog:

41
41 Cited Publications
Cat. No.: HY-15312
CAS No.: 857064-38-1
Pureté:  99.77%
Target:  

STAT JAK Apoptosis

Domaines de recherche:  

Cancer

WP1066 is an inhibitor of JAK2 and STAT3, and also shows effect on STAT5 and ERK1/2, without affecting JAK1 and JAK3. WP1066 can cross the blood-brain barrier[1][2][3][4].
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Cat. No.: HY-P11909
Domaines de recherche:  

Infection

3-WP is a linear 20-peptide with a C-terminal amidation modification. 3-WP acts on lipoteichoic acid (LTA) and disrupts cell wall permeability, induces intracellular reactive oxygen species (ROS) accumulation in a dose-dependent manner, and simultaneously inhibits respiratory chain dehydrogenase activity and intracellular ATP synthesis, thereby interfering with bacterial energy metabolism and exerting Bacterial antibacterial effects. The combination of 3-WP and Melittin (HY-P0233) exerts synergistic antibacterial effects against Gram-positive bacteria, reduces the required dosage of Melittin, and thus improves the cell selectivity of Melittin. 3-WP can serve as a peptide adjuvant for Melittin in food storage scenarios. 3-WP can be used in the research of foodborne diseases caused by methicillin-resistant Staphylococcus aureus .
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Cat. No.: HY-129341
CAS No.: 951693-87-1
Target:  

JAK STAT c-Myc

Domaines de recherche:  

Neurological Disease Cancer

WP1193 is a novel JAK2/STAT3 pathway inhibitor. WP1193 suppresses phosphorylation of JAK2 and STAT3. WP1193 decreases expression of stem cell markers including CD133 and c-myc. WP1193 can be used in the research of glioblastoma .
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