951693-87-1
951693-87-1
Chemical Structure
WP1193
- CAS No.: 951693-87-1
- Formula:C19H16BrN3O
- Molecular Weight:382.25
IUPAC Name: (S,E)-3-(6-bromopyridin-2-yl)-2-cyano-N-(cyclopropyl(phenyl)methyl)acrylamide
InChIKey: TZISYUGHDFOMLF-HAZIXKIPSA-N
SMILES: O=C(N[C@@H](C1CC1)C2=CC=CC=C2)/C(C#N)=C/C3=NC(Br)=CC=C3
Biological Activity: WP1193 is a novel JAK2/STAT3 pathway inhibitor. WP1193 suppresses phosphorylation of JAK2 and STAT3. WP1193 decreases expression of stem cell markers including CD133 and c-myc. WP1193 can be used in the research of glioblastoma[1].
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WP1193 | WP1193 is a novel JAK2/STAT3 pathway inhibitor. WP1193 suppresses phosphorylation of JAK2 and STAT3. WP1193 decreases expression of stem cell markers including CD133 and c-myc. WP1193 can be used in the research of glioblastoma. | |||||||||||||||||||||
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References
Keywords
