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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
4 Results for "
36622-29-4
" in MedChemExpress (MCE) Product Catalog:
Products (4)
4 Results for "36622-29-4" in MCE Product Catalog:
Cat. No.: HY-136907
CAS No.: 36622-29-4
Synonyms: (S)-(-)-Verapamil
Target:
Research Areas:
(S)-Verapamil ((S)-(-)-Verapamil) is an orally active MRP1 (ABCC1) modulator with a Kd value of 113 nM for hamster MRP1. (S)-Verapamil regulates MRP1, promotes MRP1-mediated glutathione efflux and the transport of calcein and leukotriene C4, reverses glutathione-activated MRP1 ATPase activity, and ultimately depletes intracellular glutathione and induces cell death. (S)-Verapamil specifically induces apoptosis in MRP1-overexpressing tumor cells. (S)-Verapamil can be used in research related to cancer, cardiac diseases such as supraventricular arrhythmia, and hypertension .
Synonyms: (S)-(-)-Verapamil hydrochloride
Research Areas:
(S)-Verapamil hydrochloride (S(-)-Verapamil hydrochloride) inhibits leukotriene C4 (LTC4) and calcein transport by MRP1. (S)-Verapamil hydrochloride leads to the death of potentially resistant tumor cells .
Cat. No.: HY-135336AS1
CAS No.: 1329611-24-6
Synonyms: (S)-(-)-Verapamil-d6 (hydrochloride)
Cat. No.: HY-136907S
CAS No.: 1398112-33-8
Synonyms: (S)-(-)-Verapamil-d3 (hydrochloride)
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
