2 Results for "

75715-89-8

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "75715-89-8" in MCE Product Catalog:

1
Leukotriene E4
Leukotriene E4
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1 Cited Publications
Cat. No.: HY-113465
CAS No.: 75715-89-8
Purity:  99.80%
Synonyms: LTE4
Category:  

Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields Inflammation/Immunology

Target:  

Endogenous Metabolite

Leukotriene E4 (LTE4) is produced by the action of dipeptidase on LTD4. Leukotriene E4 is one of the constituents of slow-reacting substance of anaphylaxis (SRS-A). Leukotriene E4 accumulates in both plasma and urine and urinary excretion of Leukotriene E4 is most often used as an indicator of asthma.
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Leukotriene E4-d5
Leukotriene E4-d5
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Cat. No.: HY-113465S
CAS No.: 1240398-14-4
Synonyms: LTE4-d5
Leukotriene E4-d5 (LTE4-d5) is the d-5-labeled Leukotriene E4 (HY-113465). Leukotriene E4 is a stable final metabolite of cysteinyl leukotrienes, produced by immune cells such as mast cells and eosinophils. Leukotriene E4 serves as a key biomarker for evaluating asthma severity, Aspirin (HY-14654) sensitivity, and mast cell activation disorders. Leukotriene E4 is a full functional agonist of CysLT1R, which induces sustained intracellular calcium mobilization and Erk phosphorylation. Leukotriene E4 mediates inflammation in a P2Y12 receptor-dependent manner. Leukotriene E4 can be used in the research of asthma and non-steroidal anti-inflammatory drug-exacerbated respiratory diseases .
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