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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
A 1210477
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "A 1210477" in MCE Product Catalog:
20
20 Cited Publications
Target:
Research Areas:
A-1210477 is a potent and selective inhibitor of MCL-1 with a Ki of 0.45 nM . A-1210477 specifically binds MCL-1 and promotes apoptosis of cancer cells in an MCL-1-dependent manner .
Cat. No.: HY-164453
CAS No.: 2228052-38-6
Target:
Research Areas:
A-1248767 is a MCL-1 inhibitor (IC50=23.9 nM; Ki=0.41 nM) with anticancer activity. A-1248767, a derivative of A-1210477 (HY-12468), binds to MCL-1 with high affinity, induces the increase of intracellular MCL-1 protein, and promotes tumor cell apoptosis .
Cat. No.: HY-125908
CAS No.: 2351218-72-7
Synonyms: PROTAC Mcl1-binding moiety 1
Research Areas:
A-1210477-piperazinyl is a compound binds to protein myeloid cell leukemia 1 (MCL1) used for PROTAC technology .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
