1 Result for "

ADAM17-IN-1

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "ADAM17-IN-1" in MCE Product Catalog:

Cat. No.: HY-175876
CAS No.: 1802395-34-1
Target:  

MMP Interleukin Related

Research Areas:  

Inflammation/Immunology

ADAM17-IN-1 is a selective inhibitor of ADAM17. ADAM17-IN-1 inhibits ADAM17 activity to reduce metabolic activity of dendritic cells (DCs), impair DC antigen-presenting function, suppress allergen-specific Th2 cell polarization, and reduce Th2 cytokine (IL-4, IL-5, IL-13) secretion. ADAM17-IN-1 demonstrates protective efficacy against house dust mite (HDM)-induced type 2/eosinophilic airway inflammation in mice. ADAM17-IN-1 can be used for the study of type 2-high allergic asthma .
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