1 Result for "

ADX68692

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "ADX68692" in MCE Product Catalog:

Art. -Nr.: HY-W673613
CAS. Nr.: 1067191-08-5
Target:  

Estrogen Receptor/ERR

Forschungsgebiete:  

Metabolic Disease

ADX68692 is an orally active negative allosteric modulators of follicle-stimulating hormone receptor with a log IC50 of -5.71. ADX68692 can inhibit hCG-induced cAMP production and s ß-arrestin 2 recruitment in HEK293 cells. ADX68692 exhibits a partial effect in both mLTC-1 and primary rat Leydig cells. ADX68692 inhibits FSHR-promoted cAMP, progesterone and estradiol production. ADX68692 can reduce the number of oocytes recovered from the ampullae .
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