2 Results for "

AG538

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "AG538" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-135680
CAS No.: 1094048-77-7
Purity:  98.03%
Synonyms: I-OMe-AG 538
Target:  

IGF-1R

Research Areas:  

Metabolic Disease Cancer

I-OMe-Tyrphostin AG 538 (I-OMe-AG 538) is a specific inhibitor of IGF-1R (insulin-like growth factor-1 receptor tyrosine kinase). I-OMe-Tyrphostin AG 538 inhibits IGF-1R-mediated signaling and is preferentially cytotoxic to nutrient-deprived PANC1 cells.?I-OMe-Tyrphostin AG 538 is an ATP-competitive inhibitor of phosphatidylinositol-5-phosphate 4-kinase α (PI5P4Kα), with an IC50?of 1 μM .
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Cat. No.: HY-135436
CAS No.: 133550-18-2
Purity:  99.80%
Target:  

IGF-1R

Research Areas:  

Cancer

AG 538 is a potent, competitive inhibitor of IGF-1 receptor kinase, with an IC50 of 400 nM .
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