2 Results for "

AK01

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "AK01" in MCE Product Catalog:

3
3 Cited Publications
Cat. No.: HY-114258
CAS No.: 1919888-06-4
Purity:  99.48%
Synonyms: AK-01
Target:  

Aurora Kinase Apoptosis

Research Areas:  

Cancer

LY3295668 (AK-01) is a highly specific and orally active inhibitor of Aurora-A kinase with a Ki values for AurA and AurB of 0.8 nM and 1038 nM respectively. LY3295668 can effectively inhibit the autophosphorylation of AurA, induce mitotic arrest and apoptosis. LY3295668 avoids the formation of polyploids related to AurB inhibition. LY3295668 can be used for the study of small cell lung cancer .
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Cat. No.: HY-114258A
CAS No.: 1919888-07-5
Synonyms: AK-01 erbumine
Target:  

Aurora Kinase Apoptosis

Research Areas:  

Cancer

LY3295668 (AK-01) erbumine is a highly specific and orally active inhibitor of Aurora-A kinase with a Ki values for AurA and AurB of 0.8 nM and 1038 nM respectively. LY3295668 erbumine can effectively inhibit the autophosphorylation of AurA, induce mitotic arrest and apoptosis. LY3295668 erbumine avoids the formation of polyploids related to AurB inhibition. LY3295668 erbumine can be used for the study of small cell lung cancer .
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