1 Result for "

ALG055009

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "ALG055009" in MCE Product Catalog:

Cat. No.: HY-168046
CAS No.: 2542029-03-6
Research Areas:  

Metabolic Disease

ALG-055009 is a selective and orally active Thyroid Hormone Receptor Beta (THR-β) agonist with an EC50 of 0.063 μM. ALG-055009 binds to the T3 hormone pocket of human THR-β, forming polar interactions with protein residues. ALG-055009 can lower total cholesterol levels in rats on a high-fat diet. ALG-055009 exhibits high metabolic stability, good permeability, a long in vivo half-life, and limited drug-drug interaction liability. ALG-055009 can be used in studies related to metabolic dysfunction-associated fatty liver disease .
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