1 Result for "

ALR27

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "ALR27" in MCE Product Catalog:

Cat. No.: HY-155408
CAS No.: 903639-13-4
Target:  

FLAP

Research Areas:  

Inflammation/Immunology

ALR-27 is an antagonist of the 5-lipoxygenase (5-LOX) activating protein FLAP and has anti-inflammatory activity. ALR-27 potently inhibits 5-LOX product formation (>80%) in pro-inflammatory M1-MDM, with no significant direct inhibition of 5-LOX. ALR-27 not only reduces prostaglandin and leukotriene (LT) production in neutrophils but also increases the production of specialized prolytic mediators in specific human macrophage phenotypes .
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