1 Result for "

AM-0687

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "AM-0687" in MCE Product Catalog:

Cat. No.: HY-120471
CAS No.: 1259522-94-5
Target:  

PI3K

Research Areas:  

Inflammation/Immunology

AM-0687 is a selective inhibitor for PI3Kδ with an IC50 of 2.9 nM. AM-0687 decreases the levels of IgG and IgM specific antibodies, inhibits the anti-IgM/CD40L-induced proliferation of human B cell (IC50=0.8 nM) and the phosphorylation of AKT (IC50=0.7 nM), and exhibits anti-inflammatory efficacy .
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