1 Result for "

AN15368

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "AN15368" in MCE Product Catalog:

Cat. No.: HY-153238
CAS No.: 2152662-92-3
Target:  

Parasite mRNA

Research Areas:  

Infection

AN15368 is an orally active trypanocidal agent and a prodrug of AN14667. AN15368 selectively targets CPSF3-mediated mRNA maturation in intracellular amastigotes of Trypanosoma cruzi, reducing the mRNA levels of the parasite. As a prodrug, AN15368 can be cleaved into its active carboxylate form by CBP of Trypanosoma cruzi. AN15368 completely clears long-term naturally acquired Trypanosoma cruzi infections in non-human primates. AN15368 can be used in the research of Chagas disease .
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