1 Result for "

AP23464

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "AP23464" in MCE Product Catalog:

Cat. No.: HY-10638
CAS No.: 845895-51-4
Target:  

c-Kit Apoptosis

Research Areas:  

Cancer

AP23464 is an ATP-based inhibitor for Kit, that inhibits the phosphorylation of Kit wildtype and mutants, with IC50 of 5-85 nM. AP23464 inhibits the proliferation of Kit mutated cells (IC50 is 3-20 nM), arrests the cell cycle at G0/G1 phase, and induces apoptosis in Kit mutated cells .
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