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APH-IN-1

" in MedChemExpress (MCE) Product Catalog:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-P11825
    APH-IN-1

    		Bacterial Infection
    APH-IN-1 is an Aminoglycoside phosphotransferase (APH) inhibitor with a Kd values of 63 nM against Escherichia coli APH(3′)-Ia. APH-IN-1 binds primarily to the ATP-binding pocket of APH in an ATP-competitive manner, with binding affinity enhanced by divalent metal ions (Mg 2+ and Ca 2+). APH-IN-1 can be used for the research of aminoglycoside-resistant bacterial infections [1].
    APH-IN-1

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