1 Result for "

APH-IN-1

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "APH-IN-1" in MCE Product Catalog:

Cat. No.: HY-P11825
Target:  

Bacterial

Research Areas:  

Infection

APH-IN-1 is an Aminoglycoside phosphotransferase (APH) inhibitor with a Kd values of 63 nM against Escherichia coli APH(3′)-Ia. APH-IN-1 binds primarily to the ATP-binding pocket of APH in an ATP-competitive manner, with binding affinity enhanced by divalent metal ions (Mg 2+ and Ca 2+). APH-IN-1 can be used for the research of aminoglycoside-resistant bacterial infections [1].
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