2 Results for "

APP modulator-1

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "APP modulator-1" in MCE Product Catalog:

Cat. No.: HY-180856
CAS No.: 299420-64-7
Target:  

Amyloid-β

Research Areas:  

Neurological Disease

APP modulator-1 is an APP modulator.
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Cat. No.: HY-183057
CAS No.: 2234900-83-3
GRK2 modulator 1 is an orally active, brain-penetrant and selective GRK2 modulator. GRK2 modulator 1 enhances the active, non-phosphorylated GRK2 and prevents mitochondrial GRK2 and TOMM6 aggregation. GRK2 modulator 1 enhances the non-amyloidogenic processing of APP and prevent PHF-tau, neurodegeneration, and neuronal loss. GRK2 modulator 1 decreases the senescence marker, UPAR, reduces the Alzheimer disease (AD)-related mortality, and prolongs survival. GRK2 modulator 1 exerts neuroprotection by inhibiting HDAC6, and counteracts age-related cardiac dysfunction. GRK2 modulator 1 can be used for research on AD .
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