1 Result for "

ARGX111

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "ARGX111" in MCE Product Catalog:

Cat. No.: HY-P991660

Target:  

c-Met/HGFR

Research Areas:  

Cancer

ARGX-111 is an anti-MET antibody. ARGX-111 blocks HGF-dependent and -independent signaling, downregulating MET expression on the tumor cell surface. ARGX-111 depletes MET-expressing circulating tumor cells through enhanced antibody-dependent cell-mediated cytotoxicity (ADCC), thereby inhibiting tumor metastasis. ARGX-111 depletes circulating tumor cells and inhibits bone and lung metastasis in an orthotopic mouse model of metastatic breast cancer. ARGX-111 is promising for research in breast cancer and other cancers .
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