ARGX-111

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Based on 1 Customer Validation

ARGX-111 is an anti-MET antibody. ARGX-111 blocks HGF-dependent and -independent signaling, downregulating MET expression on the tumor cell surface. ARGX-111 depletes MET-expressing circulating tumor cells through enhanced antibody-dependent cell-mediated cytotoxicity (ADCC), thereby inhibiting tumor metastasis. ARGX-111 depletes circulating tumor cells and inhibits bone and lung metastasis in an orthotopic mouse model of metastatic breast cancer. ARGX-111 is promising for research in breast cancer and other cancers.

For research use only. We do not sell to patients.

  • Purity: 99.25%
  • Molecular Weight:144.88 kDa
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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100 mg

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