1 Result for "

ARQ069

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "ARQ069" in MCE Product Catalog:

Cat. No.: HY-101544
CAS No.: 1314021-57-2
Target:  

FGFR

Research Areas:  

Cancer

ARQ 069, an analog of ARQ 523, inhibits FGFR in an enantiospecific manner. ARQ 069 targets the unphosphorylated, inactive forms of FGFR1/FGFR2 kinases (IC50s of 0.84 μM and 1.23 μM, respectively). ARQ 069 inhibits FGFR1/FGFR2 autophosphorylation (IC50s of 2.8 and 1.9 μM, respectively) through a mechanism in a non-ATP competitive dependent manner .
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