1 Result for "

ARRY-440

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "ARRY-440" in MCE Product Catalog:

Cat. No.: HY-159795
CAS No.: 2754408-94-9
Synonyms: PF-07799933; ARRY-440
Target:  

Raf PERK

Research Areas:  

Cancer

Claturafenib ( PF-07799933) is an orally active inhibitor of pan-mutant BRAF. Claturafenib inhibits pERK in cells (IC50 value of 1.6 nM in HT29 cells). Claturafenib has anticancer activity against BRAF G469A mutant NSCLC and BRAF K601E mutant melanoma .
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