1 Result for "

ARV393

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "ARV393" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-158105
CAS No.: 2851885-95-3
Purity:  99.43%
Target:  

PROTACs BCL6 CD20 IFNAR

Research Areas:  

Cancer

ARV-393 is a BCL6 PROTAC degrader. ARV-393 forms a complex with BCL6 and Cereblon, induces BCL6 ubiquitination, and mediates BCL6 degradation via the ubiquitin-proteasome system. ARV-393 enhances CD20 expression, interferon pathway activity and antigen presentation. ARV-393 induces tumor growth inhibition and regression. ARV-393 can be used in research related to non-Hodgkin's lymphoma, high-grade B-cell lymphoma, diffuse large B-cell lymphoma, Burkitt's lymphoma and follicular lymphoma .
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