1 Result for "

Aiphanol

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "Aiphanol" in MCE Product Catalog:

(±)-Aiphanol
(±)-Aiphanol
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Cat. No.: HY-152120
CAS No.: 578020-29-8
Synonyms: Aiphanol
Category:  

Arecaceae Phenols Polyphenols Plants Aiphanes aculeata Willd

Target:  

COX VEGFR

(±)-Aiphanol is a newly discovered stilbenolignan analog. (±)-Aiphanol exhibits significant anti-inflammatory activity, acting through inhibition of COX-1 and COX-2. The inhibitory effect on COX-1 (IC50 = 1.9 μM) is particularly strong, while the effect on COX-2 (IC50= 9.9 μM) is relatively weak [1].(±)-Aiphanol effectively inhibits VEGFR2 (IC50=0.92 μM). (±)-Aiphanol blocks angiogenesis and promotes apoptosis through inhibition of VEGFR2 and COX2 activity. (±)-Aiphanol is orally active .
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