2 Results for "

Airway hyperreactivity model

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Airway hyperreactivity model" in MCE Product Catalog:

4
FR900359
FR900359
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4 Cited Publications
Cat. No.: HY-117037
CAS No.: 107530-18-7
Purity:  99.90%
Category:  

Ardisia crenata Sims Ketones, Aldehydes, Acids Plants Myrsinaceae

Target:  

Apoptosis ERK

FR900359 is a depsipeptide selective inhibitor of Gαq/11/14 in mammalia, can inhibits ERK pathway. FR900359 suppresses the proliferation of melanoma cells and decreases of blood pressure. FR900359 also protected against airway hyperreactivity in murine models of allergen sensitization in Ovalbumin, low endotoxin (HY-W250978A)-induced sensitization model of asthma. FR900359 can be used for cancer and cardiovascular disease research .
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3-O-Methylquercetin
3-O-Methylquercetin
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Cat. No.: HY-N1860
CAS No.: 1486-70-0
Category:  

Flavonoids Flavones Aconitum apetalum (Huth) B. Fedtsch. Plants Rhamnaceae Disease Research Fields Inflammation/Immunology

Target:  

Phosphodiesterase (PDE) NO Synthase

3-O-Methylquercetin is an inhibitor of cAMP and CGMP-phosphodiesterase (PDE) with IC50 at 13.8 μM and 14.3 μM, respectively. 3-O-Methylquercetin is an inhibitor of β-secretase with an IC50 of 6.5 μM. 3-O-Methylquercetin has a neuroprotective effect against neuronal death caused by oxidative damage. 3-O-Methylquercetin has strong antiviral activity against poliovirus, coxsackie virus and human rhinovirus. 3-O-Methylquercetin has anti-inflammatory and trachea-relaxing effects and can be used in the study of inflammatory diseases and asthma .
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