1 Result for "

Aloesone

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "Aloesone" in MCE Product Catalog:

Cat. No.: HY-N8559
CAS No.: 40738-40-7
Aloesone is an orally active phenolic heptaketide natural product that can cross the blood-brain barrier. Aloesone inhibits LPS-induced oxidative stress, inflammation, M1 polarization and apoptosis in RAW264.7 macrophages by reducing ROS production and NO release, and downregulating the mRNA expression of iNOS, IL-1β and TNF-α. Aloesone also inhibits glutamate-induced neuronal damage and pentylenetetrazol (PTZ)-induced seizures by activating c-SRC .
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