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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
Ames+test
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "Ames+test" in MCE Product Catalog:
Cat. No.: HY-N5054
CAS No.: 1277188-85-8
Category:
other families Flavonoids Flavonones Plants Disease Research Fields Inflammation/Immunology
Target:
Cat. No.: HY-W585867
CAS No.: 132898-07-8
Target:
Research Areas:
4,7,8-TriMeIQx is a mutagenic imidazoquinoxaline and chemical in bacterial systems (Ames test) as well as active in the DNA repair test in liver cells.
Cat. No.: HY-182366
Target:
Research Areas:
EED-IN-5 is an orally active, EZH2-selective trisubstituted pyridine-based EED-H3K27me3 inhibitor and immunomodulator with anti-inflammatory activity. The IC50 value of EED-IN-5 against EED is 28.21 nM. In mouse models, EED-IN-5 preferentially and persistently accumulates in lymph nodes after oral administration. By reducing the H3K27me3 level of dendritic cells and inhibiting their migration, EED-IN-5 decreases the infiltration of specific dendritic cells, macrophages and T cells into the spinal cord and brain. EED-IN-5 exhibits hERG inhibitory activity, shows negative results in the Mini-Ames test, and causes no obvious toxicity upon long-term high-dose administration. EED-IN-5 can be used for the research of multiple sclerosis .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
