2 Results for "

Antituberculosis agent7

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Antituberculosis agent7" in MCE Product Catalog:

Cat. No.: HY-152137
CAS No.: 2874263-73-5
Research Areas:  

Infection Inflammation/Immunology

Antituberculosis agent-7, an oxetanyl-quinoline derivative, has shown good antibacterial activity against P. mirabilis with a MIC of 31.25 μM. Antituberculosis agent-7 shows good antifungal activity against A. niger with a MIC of 62.5 μM. Antituberculosis agent-7 shows excellent antimycobacterial activity with MIC 3.41 μM for M. tuberculosis H37Rv .
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Cat. No.: HY-163107
Target:  

Bacterial

Research Areas:  

Infection

Antimycobacterial agent-7 (compound 4) is a 1,2,4-triazole anti-tuberculosis agent (MIC: 2 μg/mL). Antimycobacterial agent-7 inhibits Mtb KatG and causes the accumulation of ROS in Mtb cells. ROS produces oxidative damage, leading to the death of Mtb .
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