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Aroclor 1254

" in MedChemExpress (MCE) Product Catalog:

By Targets:	DNA/RNA Synthesis (1) Drug Metabolite (1) Endogenous Metabolite (1) Reactive Oxygen Species (ROS) (1)
By Research Areas:	Metabolic Disease (3) Neurological Disease (1)

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Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-154918

LysoPE(18:2/0:0)	Drug Metabolite	Metabolic Disease
LysoPE (18:2/0:0) is a lysophosphatidylethanolamine implicated in phospholipid metabolism. LysoPE (18:2/0:0) shows significantly altered serum levels in mice exposed to a combination of DEHP (HY-B1945) and Aroclor 1254, which is associated with disturbed phospholipid metabolism. LysoPE (18:2/0:0) can be used for the research of endocrine-disrupting compound-induced metabolic disorders and lipid metabolism disturbance. LysoPE (18:2/0:0) is identified as a potential biomarker for the combined toxicity of DEHP and Aroclor 1254 .

HY-128431

Arochlor 1254	Reactive Oxygen Species (ROS)	Neurological Disease Metabolic Disease
Arochlor 1254 is a polychlorinated biphenyl (PCB) mixture with biphenyl and 54% chlorine. Aroclor 1254 reduced cell viability and induced overproduction of intracellular reactive oxygen species in a dose-dependent manner. Arochlor 1254 exposure reduces calcium homeostasis, osteoblast differentiation and bone formation .

HY-133610

3,4,6-Trichlorocatechol	DNA/RNA Synthesis	Others
3,4,6-trichlorocatechol (TCC) is the metabolite produced by industrial pollutant through post-mitochondrial liver fraction from Aroclor-1254 induced rats .

HY-W209558

Acoramone 2,4,5-Trimethoxyphenylacetone	Endogenous Metabolite	Metabolic Disease
Acoramone (2,4,5-Trimethoxyphenylacetone) is a natural product that can be isolated from phenylpropane. Acoramone is one of the main metabolites identified in the ¹H NMR spectrum of fraction b of the supernatant from the incubation of liver microsomes from Aroclor 1254-pretreated rats .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-W209558

Acoramone 2,4,5-Trimethoxyphenylacetone	Natural Products Araceae Acorus calamus L. Plants Source Classification	Endogenous Metabolite
Acoramone (2,4,5-Trimethoxyphenylacetone) is a natural product that can be isolated from phenylpropane. Acoramone is one of the main metabolites identified in the ¹H NMR spectrum of fraction b of the supernatant from the incubation of liver microsomes from Aroclor 1254-pretreated rats .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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Aroclor 1254

Inhibitors & Agonists

NaturalProducts

Natural
Products