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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
B. dothidea
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "B. dothidea" in MCE Product Catalog:
Cat. No.: HY-149614
CAS No.: 2991094-41-6
Target:
Cat. No.: HY-162488
Laccase-IN-3 (Compound 2b) is a laccase inhibitor (IC50 = 1.02= μM) with significant antifungal activity. Laccase-IN-3 shows superior inhibitory effect on Botryosphaeria dothidea (EC50 = 0.17 mg/L). Laccase-IN-3 effectively blocks the catalytic function of laccase by binding to its active center. Laccase-IN-3 also disrupts pathogen cell membrane integrity and increases ROS .
Cat. No.: HY-170378
Laccase-IN-5 (Compound 2b) is the inhibitor for Laccase with an IC50 of 0.82 μM. Laccase-IN-5 increases the cell membrane permeability, limits the growth of hyphae, destorys the cell wall, and induces oxidative stress responses. Laccase-IN-5 exhibits antifungal activity against various plant pathogenic fungi and oomycetes, inhibits B. dothidea with an EC50 of 0.96 mg/L .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
