1 Result for "

BAY1179470

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "BAY1179470" in MCE Product Catalog:

Cat. No.: HY-P99007
CAS No.: 1634620-63-5
Synonyms: BAY 1179470

Target:  

FGFR

Research Areas:  

Cancer

Aprutumab (BAY 1179470) is a fully human fibroblast growth factor receptor 2 (FGFR2)-specific monoclonal antibody . Aprutumab induces FGFR2 endocytosis and degradation in cancer cells expressing FGFR2. Aprutumab serves as the targeted monoclonal antibody component of the antibody-drug conjugate BAY 1187982 (HY-141600) and mediates the endocytosis of the antibody-drug conjugate into FGFR2-positive cells. Aprutumab can be used for the research of FGFR2-positive solid tumors, including studies on gastric cancer and triple-negative breast cancer .
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