1 Result for "

BMS182123

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "BMS182123" in MCE Product Catalog:

Trichodimerol
Trichodimerol
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Cat. No.: HY-N12104
CAS No.: 145174-90-9
Synonyms: BMS-182123
Category:  

Natural Products Endogenous metabolite

Target:  

TNF Receptor

Trichodimerol (BMS-182123) is a TNF-α promoter inhibitor that inhibits the activity of lipopolysaccharide-induced cytokine secretion. Trichodimerol inhibits lipopolysaccharide-induced TNF-α promoter activity, reduces steady-state TNF-α mRNA expression, and does not alter the stability of TNF-α mRNA. Trichodimerol inhibits lipopolysaccharide-induced TNF-α secretion in murine and human immune cells. Trichodimerol reduces lipopolysaccharide-induced IL-1β secretion by 25%-50% in vitro. Trichodimerol does not alter total protein synthesis or constitutive lysozyme secretion at effective concentrations. Trichodimerol can be used for the research of septic shock .
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