1 Result for "

BMS767778

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "BMS767778" in MCE Product Catalog:

Cat. No.: HY-16656
CAS No.: 915729-95-2
Target:  

Dipeptidyl Peptidase

Research Areas:  

Metabolic Disease Cancer

BMS-767778 is an orally active and selective DPP4 inhibitor with Ki values of 0.94 nM, 4.9, 3.2 nM for DPP4, DPP8 and DPP9 respectively. BMS-767778 exhibits >3,000-fold selectivity over the related enzymes DPP8 and DPP9. BMS-767778 inhibits CYP-3A4 with IC50 of 5.2 μM. BMS-767778 significantly reduces blood glucose levels in high fat fed (HFD) ob/ob mice with safety profile. BMS-767778 can be used for diabetes mellitus research .
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