1 Result for "

BPU17

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "BPU17" in MCE Product Catalog:

Cat. No.: HY-162904
CAS No.: 2198977-68-1
Research Areas:  

Cardiovascular Disease

BPU17 binds to PHB1 and causes mild defects in mitochondrial function by defects in the PHB1-PHB2 interaction. This impairment inhibits the SRF/CArG-box-dependent transcription, resulting in the suppression of epithelial-mesenchymal transition (EMT) of retinal pigment epithelial cells (RPEs). BPU17 exhibits antifibrotic activity in vivo. BPU17 is promising for research of anti-neovascular age-related macular degeneration (nAMD) agent .
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