2198977-68-1
Chemical Structure
BPU17
- CAS No.: 2198977-68-1
- Formula:C12H13ClN2O2
- Molecular Weight:252.70
InChIKey: PQBOODMFLJIYSP-UHFFFAOYSA-N
SMILES: ClC1=CC=C(NC(NC(C2CCC2)=O)=O)C=C1
Biological Activity: BPU17 binds to PHB1 and causes mild defects in mitochondrial function by defects in the PHB1-PHB2 interaction. This impairment inhibits the SRF/CArG-box-dependent transcription, resulting in the suppression of epithelial-mesenchymal transition (EMT) of retinal pigment epithelial cells (RPEs). BPU17 exhibits antifibrotic activity in vivo. BPU17 is promising for research of anti-neovascular age-related macular degeneration (nAMD) agent[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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BPU17 | 98.16% | BPU17 binds to PHB1 and causes mild defects in mitochondrial function by defects in the PHB1-PHB2 interaction. This impairment inhibits the SRF/CArG-box-dependent transcription, resulting in the suppression of epithelial-mesenchymal transition (EMT) of retinal pigment epithelial cells (RPEs). BPU17 exhibits antifibrotic activity in vivo. BPU17 is promising for research of anti-neovascular age-related macular degeneration (nAMD) agent. | ||||||||||||||||||||
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