1 Result for "

BRD6989

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "BRD6989" in MCE Product Catalog:

2
2 Cited Publications
Cat. No.: HY-122586
CAS No.: 642008-81-9
Purity:  99.56%
Target:  

CDK Interleukin Related

Research Areas:  

Inflammation/Immunology

BRD6989, an analog of the natural product cortistatin A (dCA), inhibits CDK8 and upregulates IL-10. BRD6989 selectively binds a complex of CDK8 with an IC50 of ~200 nM. BRD6989 inhibits the kinase activity of recombinant CDK8 or CDK19 complexes .
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