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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2 Results for "
BTBR islets
" in MedChemExpress (MCE) Product Catalog:
Products (2)
2 Results for "BTBR islets" in MCE Product Catalog:
1
1 Cited Publications
Cat. No.: HY-W017387
CAS No.: 4502-00-5
Synonyms: Sodium 4-methyl-2-oxopentanoate; 2-Ketoisocaproic acid sodium salt
Research Areas:
Sodium α-ketoisocaproate (Sodium 4-methyl-2-oxopentanoate) is an insulin secretagogue. Sodium α-ketoisocaproate undergoes transamination catalyzed by BCAT and BCATm to produce α-ketoglutarate and leucine; it also binds to the SUR1 site to inhibit KATP channel activity, but does not directly affect the Kir6.2 subunit. Sodium α-ketoisocaproate regulates Ca 2+ influx. Sodium α-ketoisocaproate exerts insulinotropic activity in pancreatic islets and intact mouse pancreata with sufficient BCATm expression. Sodium α-ketoisocaproate can be used in research related to type 2 diabetes .
Cat. No.: HY-W017387S
CAS No.: 93523-67-2
Synonyms: Sodium 4-methyl-2-oxopentanoate-d3; 2-Ketoisocaproic acid-d3 sodium salt
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
