3 Results for "

Bafetinib

" in MedChemExpress (MCE) Product Catalog:
Products (3)

3 Results for "Bafetinib" in MCE Product Catalog:

14
14 Cited Publications
Cat. No.: HY-50868
CAS No.: 859212-16-1
Synonyms: INNO-406; NS-187
Target:  

Bcr-Abl Src Apoptosis

Research Areas:  

Cancer

Bafetinib is an orally active Lyn/Bcr-Abl tyrosine kinase inhibitor. Bafetinib enhances the activity of several pro-apoptotic Bcl-2 homology (BH) 3-pure proteins (Bim, Bad, Bmf, and Bik) through intrinsic apoptotic pathways regulated by the Bcl-2 family, and induces apoptosis of Ph + leukemia cells. Bafetinib has antitumor activity .
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Cat. No.: HY-12039
CAS No.: 887650-05-7
Purity:  98.93%
Synonyms: Bafetinib analog
Target:  

Src

Research Areas:  

Cardiovascular Disease

Lyn-IN-1 (Bafetinib analog) is a Lyn kinase inhibitor. Lyn-IN-1 inhibits Lyn kinase activity and effectively increases platelet count. Lyn-IN-1 is an analog of Bafetinib (HY-50868). Lyn-IN-1 can be used for the research of thrombocytopenia .
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Cat. No.: HY-50868R
CAS No.: 859212-16-1
Synonyms: INNO-406 (Standard); NS-187 (Standard)
Research Areas:  

Cancer

Bafetinib (Standard) is the analytical standard of Bafetinib. This product is intended for research and analytical applications. Bafetinib is an orally active Lyn/Bcr-Abl tyrosine kinase inhibitor. Bafetinib enhances the activity of several pro-apoptotic Bcl-2 homology (BH) 3-pure proteins (Bim, Bad, Bmf, and Bik) through intrinsic apoptotic pathways regulated by the Bcl-2 family, and induces apoptosis of Ph+ leukemia cells. Bafetinib has antitumor activity .
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