1 Result for "

Besigliptin

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "Besigliptin" in MCE Product Catalog:

Cat. No.: HY-139792
CAS No.: 1177460-72-8
Synonyms: SHR117887
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

Besigliptin tosylate (SHR117887) is a DPP-4 inhibitor with activity to improve metabolic control and β-cell function. Besigliptin tosylate can effectively reduce serum DPP-4 activity and improve oral glucose tolerance. Besigliptin tosylate significantly reduces fasting blood glucose levels and improves lipid profiles in a diabetic mouse model. The effect of besigliptin tosylate is comparable to that of the known compound vildagliptin (HY-14291) at the same concentration. Besigliptin tosylate increases insulin staining of pancreatic islet cells in chronic administration, indicating improved β-cell function .
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