55 Results for "

C+terminus

" in MedChemExpress (MCE) Product Catalog:
Products (55)

55 Results for "C+terminus" in MCE Product Catalog:

5
Gap19
Gap19
0 Images
5 Cited Publications
Cat. No.: HY-P1136
CAS No.: 1507930-57-5
Target:  

Gap Junction Protein

Research Areas:  

Cardiovascular Disease

Gap19, a peptide derived from nine amino acids of the Cx43 cytoplasmic loop (CL), is a potent and selective connexin 43 (Cx43) hemichannel blocker. Gap19 inhibits hemichannels caused by preventing intramolecular interactions of the C-terminus (CT) with the CL. Gap19 is not blocking GJ channels or Cx40/pannexin-1 hemichannels. Gap19 has protective effects against myocardial .
5
Gap19 TFA
Gap19 TFA
0 Images
5 Cited Publications
Cat. No.: HY-P1136A
Target:  

Gap Junction Protein

Research Areas:  

Cardiovascular Disease

Gap19 TFA, a peptide derived from nine amino acids of the Cx43 cytoplasmic loop (CL), is a potent and selective connexin 43 (Cx43) hemichannel blocker. Gap19 TFA inhibits hemichannels caused by preventing intramolecular interactions of the C-terminus (CT) with the CL. Gap19 TFA is not blocking GJ channels or Cx40/pannexin-1 hemichannels. Gap19 TFA has protective effects against myocardial .
2
VCP Activator 1
VCP Activator 1
0 Images
2 Cited Publications
Cat. No.: HY-157508
CAS No.: 3061959-30-3
Purity:  99.94%
Target:  

p97

Research Areas:  

Others

VCP Activator 1 is a VCP activator that dose-dependently stimulates VCP ATPase activity. VCP Activator 1 binds an allosteric pocket near the C-terminus. In addition, VCP Activator 1 binding site can also be occupied by a phenylalanine residue in the VCP C-terminal tail .
2
Casein Kinase 2 Substrate Peptide
Casein Kinase 2 Substrate Peptide
0 Images
2 Cited Publications
Cat. No.: HY-P3815
CAS No.: 132176-35-3
Target:  

Casein Kinase

Research Areas:  

Others

Casein Kinase 2 Substrate Peptide is a common CK2 substrate peptide. Casein Kinase 2 Substrate Peptide is synthesized with its C-terminus conjugated to 5-[(2-aminoethyl)amino]naphthalene-1-sulfonic acid (EDANS). Casein Kinase 2 Substrate Peptide can be used for protein kinase CK2 activity determination .
1
T7 Tag Peptide
T7 Tag Peptide
0 Images
1 Cited Publications
Cat. No.: HY-P0327
CAS No.: 245445-88-9
Target:  

Peptides

Research Areas:  

Others

T7 Tag Peptide is a protein tag peptide composed of 11 residues from the N-terminus of gp10, the capsid protein of T7 bacteriophage. T7 Tag Peptide can be fused to the N-terminus or C-terminus of proteins such as enhanced green fluorescent protein (EGFP). T7 Tag Peptide is applicable for various immunoassays and affinity purification .
1
T7 Tag Peptide TFA
T7 Tag Peptide TFA
0 Images
1 Cited Publications
Cat. No.: HY-P0327A
Target:  

Peptides

Research Areas:  

Others

T7 Tag Peptide TFA is a protein tag consisting of 11 residues from the N-terminus of the T7 bacteriophage capsid protein gp10. T7 Tag Peptide TFA can be fused to the N-terminus or C-terminus of proteins such as enhanced green fluorescent protein (EGFP). T7 Tag Peptide TFA can be used in various immunoassays and affinity purification .
Ac-pSar12-OH
Ac-pSar12-OH
0 Images
Cat. No.: HY-P10069
CAS No.: 2313534-24-4
Target:  

Drug Intermediate ADC Linkers

Research Areas:  

Others

Ac-pSar12-OH is a water-soluble polymer of the polysarcosine class and can be used as a linker. Ac-pSar12-OH is a linear polypeptide derivative composed of 12 arginine units. Ac-pSar12-OH N-terminus is modified with an acetyl group, while the C-terminus retains a free hydroxyl group, which can help enhance the stability of the polypeptide .
Canvuparatide
Canvuparatide
0 Images
Cat. No.: HY-P10909
CAS No.: 2925554-87-4
Synonyms: MBX 2109
Target:  

Thyroid Hormone Receptor

Research Areas:  

Endocrinology

Canvuparatide (MBX 2109) is a prodrug for parathyroid hormone (PTH) peptide that releases the bioactive PTH[1-32] peptide agonist that retains a fatty acylated lysine (Lys33) at the C-terminus, thereby extending the halflife of Canvuparatide. Canvuparatide can be used for the symptoms of hypoparathyroidism such as hypocalcemia and hyperphosphatemia .
ALFA-tag
ALFA-tag
0 Images
Cat. No.: HY-P10531
CAS No.: 2413353-86-1
Target:  

Peptides

Research Areas:  

Others

ALFA-tag is a small and stable α-helical structure composed of 15 amino acids. ALFA-tag is highly hydrophilic and can be placed at the N-terminus, C-terminus, or between two independently folded domains of the target protein without affecting the function of the protein. ALFA-tag is widely used as an epitope tag and is used for the detection and manipulation of proteins in living cells .
C5a Receptor agonist, W5Cha
C5a Receptor agonist, W5Cha
0 Images
Cat. No.: HY-P5506
CAS No.: 144555-23-7
Target:  

Complement System

Research Areas:  

Others

C5a Receptor agonist, W5Cha (Peptide 1) is a selective complement C5a receptor (C5aR) agonist (EC50=0.2 μM), a hexapeptide derived from the C-terminus of C5a with specific amino acid modifications. C5a Receptor agonist, W5Cha is able to interact with the Arg-206 site of the C5a receptor through its C-terminal arginine, thereby activating the receptor .
Transdermal Peptide Disulfide
Transdermal Peptide Disulfide
0 Images
Cat. No.: HY-P1565
CAS No.: 888486-23-5
Synonyms: TD 1 Disulfide(peptide)
Target:  

Na+/K+ ATPase

Research Areas:  

Inflammation/Immunology

Transdermal Peptide Disulfide (TD 1 Disulfide(peptide)) is a 11-amino acid peptide, binds toNa +/K +-ATPase beta-subunit (ATP1B1), and mainly interacts with the C-terminus of ATP1B1. Transdermal Peptide Disulfide can enhance the transdermal delivery of many macromolecules .
Transdermal Peptide Disulfide TFA
Transdermal Peptide Disulfide TFA
0 Images
Cat. No.: HY-P1565A
Synonyms: TD 1 Disulfide(peptide) TFA
Target:  

Na+/K+ ATPase

Research Areas:  

Others

Transdermal Peptide Disulfide TFA (TD 1 Disulfide(peptide) TFA) is a 11-amino acid peptide, binds to Na +/K +-ATPase beta-subunit (ATP1B1), and mainly interacts with the C-terminus of ATP1B1. Transdermal Peptide Disulfide TFA can enhance the transdermal delivery of many macromolecules .
LL-37, acetylated,amidated
LL-37, acetylated,amidated
0 Images
Cat. No.: HY-P1884
Target:  

Bacterial

Research Areas:  

Infection

LL-37, acetylated, amidated is a cathelicidin peptide LL-37 acetylated on the N-terminus and amidated on the C-terminus. The single human cathelicidin peptide LL-37 has antimicrobial and anti-biofilm activity against multiple Gram-positive and Gram-negative human pathogens, and has wound-healing effects on the host .
Cenderitide
Cenderitide
0 Images
Cat. No.: HY-P3624
CAS No.: 507289-11-4
Target:  

Guanylate Cyclase

Research Areas:  

Cardiovascular Disease

Cenderitide is a potent agonist of particulate guanylyl cyclase receptor (pGC). Cenderitide is a natriuretic peptide (NP) composed of C-type natriuretic peptide (CNP) fused to the C-terminus of Dendroaspis natriuretic peptide (DNP). Cenderitide activates both pGC-A and pGC-B, activates the second messenger cGMP, suppresses aldosterone, and preserves GFR without reducing blood pressure. Cenderitide can be used for heart failure research .
Rilunermin alfa
Rilunermin alfa
0 Images
Cat. No.: HY-P3385
CAS No.: 2254278-53-8
Synonyms: SCB-313

Target:  

Drug Derivative Apoptosis

Research Areas:  

Cancer

Rilunermin alfa (SCB-313) is a recombinant fusion protein composed of the human C-propeptide of alpha1(I) collagen (Trimer-Tag) to the C-terminus of the mature human tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL; Apo2L). Rilunermin alfa has potential pro-apoptotic and antineoplastic activities .
O-Glycoprotease
O-Glycoprotease
0 Images
Cat. No.: HY-E70565
Target:  

Endonuclease

Research Areas:  

Inflammation/Immunology

O-Glycoprotease is an O-glycoprotein-specific endoprotease that catalyzes the hydrolysis of peptide bonds directly adjacent to the O-polymer in native mucin-type O-glycosylated proteins. O-Glycoprotease sequence is from Akkermansia muciniphila, recombinantly expressed in E.coli, with a 6×His tag at the C-terminus.
The enzyme maintains high activity between pH 5.5-7.5 and is resistant to 1M NaCl, but is highly sensitive to EDTA (0.5 mM EDTA) and can be inhibited by Zn 2+.
PDZ1 Domain inhibitor peptide
PDZ1 Domain inhibitor peptide
0 Images
Cat. No.: HY-P1195
CAS No.: 1315378-73-4
Target:  

iGluR

Research Areas:  

Neurological Disease

PDZ1 Domain inhibitor peptide, a cyclic peptide, incorporates a β-Ala lactam side chain linker and targets the PDZ1 domains of the postsynaptic density protein 95 (PSD-95). PDZ1 Domain inhibitor peptide disrupts the GluR6/PSD-95 interaction and is very efficient in competing against the C terminus of GluR6 for the PDZ1 domain .
Eflumenibep alfa
Eflumenibep alfa
0 Images
Cat. No.: HY-P991676
CAS No.: 2418159-10-9
Synonyms: DS-2325A

Target:  

Kallikrein

Research Areas:  

Inflammation/Immunology

Eflumenibep alfa is a Kallikrein 5 inhibitor with anti-inflammatory activity. Eflumenibep alfa is a fusion protein that combines human SPINK2 with the human IgG1 Fc fragment at the C-terminus .
Efpixileukin alfa
Efpixileukin alfa
0 Images
Cat. No.: HY-P991678
CAS No.: 2996895-52-2
Synonyms: XENP-27564; XMAB-27564

Target:  

Interleukin Related

Research Areas:  

Inflammation/Immunology

Efpixileukin alfa is a fusion protein that combines human IL-2 variant fused at the C-terminus to human immunoglobulin G1 (IgG1) Fc fragment. Efpixileukin alfa is an immunomodulator .
UBD1031
UBD1031
0 Images
Cat. No.: HY-172193
Synonyms: SGC-UBD1031
Target:  

Deubiquitinase HDAC

Research Areas:  

Inflammation/Immunology Cancer

UBD1031 (SGC-UBD1031) is a selective USP16/HDAC6-UBD antagonist with a human USP16-UBD IC50 of 10.6 μM, KD value of 48 nM, and a human HDAC6-UBD KD of 16 nM. UBD1031 disrupts ISG15 C-terminus interactions with USP16-UBD and HDAC6-UBD, and exhibits cooperative inhibition of full-length USP16 deubiquitinase activity via USP16-UBD binding. UBD1031 can be used in research on cancer, autoimmune diseases, and Down syndrome .
Assay Types