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2 Results for "
CHF-3381
" in MedChemExpress (MCE) Product Catalog:
Products (2)
2 Results for "CHF-3381" in MCE Product Catalog:
Referencia número: HY-101440A
No. CAS: 202914-18-9
Synonyms: CHF-3381
Target:
Áreas de investigación:
Indantadol hydrochloride (CHF-3381) is an orally active, non-selective NMDA antagonist and MAO inhibitor. Indantadol hydrochloride blocks the binding of [³H]-MK-801 to NMDA receptors in a non-competitive manner, with an IC50 of 8.1 μM. Indantadol hydrochloride completely inhibits dopamine release caused by NMDA. Indantadol hydrochloride protects neurons, with an ED₅₀ of 35 μM. Indantadol hydrochloride has anticonvulsant and anti-high pain hypersensitivity activities .
Referencia número: HY-101440
No. CAS: 202844-10-8
Synonyms: CHF-3381 free base
Target:
Áreas de investigación:
Indantadol (the free base of CHF-3381) is an orally active, non-selective NMDA antagonist and MAO inhibitor. Indantadol blocks the binding of [³H]-MK-801 to NMDA receptors in a non-competitive manner, with an IC50 of 8.1 μM. Indantadol completely inhibits dopamine release caused by NMDA. Indantadol protects neurons, with an ED₅₀ of 35 μM. Indantadol has anticonvulsant and anti-high pain hypersensitivity activities .
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