1 Result for "

CK147

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "CK147" in MCE Product Catalog:

Cat. No.: HY-182690
CAS No.: 1883356-12-4
Target:  

HIV

Research Areas:  

Infection

CK147 is a Sec61α translocase inhibitor that blocks the co-translational translocation of proteins by binding to and inhibiting the Sec61 protein translocation channel on the endoplasmic reticulum membrane. CK147 exhibits potent CD4 downregulation activity with an IC50 of 0.04 µM. CK147 prevents HIV entry into host cells and shows significant cytotoxicity. CK147 can be used in studies related to HIV infection .
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