1 Result for "

CLEVER

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "CLEVER" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-P99236
CAS No.: 2259301-27-2
Synonyms: FP-1305
Bexmarilimab (FP-1305) is a potent humanized anti-CLEVER-1 IgG4 antibody with an IC50 value of 4.51 nM. Bexmarilimab is capable of inducing a phenotypic M2 to M1 immune switch of tumor-associated macrophages. Bexmarilimab can promote antigen presentation and pro-inflammatory cytokine secretion. Bexmarilimab can induce B-cell and T-cell activation. Bexmarilimab can be used in researches of immunology and cancer, such as colorectal carcinoma .
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