1 Result for "

CP601932

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "CP601932" in MCE Product Catalog:

Cat. No.: HY-138879B
CAS No.: 357425-68-4
Purity:  99.74%
Synonyms: (1S,5R)-CP-601927
Target:  

nAChR

Research Areas:  

Neurological Disease

CP-601932 ((1S,5R)-CP-601927) is a high-affinity partial agonist at α3β4 nAChR (Ki=21 nM; EC50=~ 3 μM). CP-601932 has the same high-binding affinity at α4β2 nAChR (Ki=21 nM) and an order of magnitude lower affinity for α6 and α7 nAChR subtypes. CP-601932 selectively decreases ethanol but not sucrose consumption and operant self-administration following long-term exposure. CP-601932 can penetrate the CNS .
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