1 Result for "

CSN5-IN-2

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "CSN5-IN-2" in MCE Product Catalog:

Cat. No.: HY-172252
Target:  

PD-1/PD-L1 RAD51

Research Areas:  

Cancer

CSN5-IN-2 (Compound 31) is a CSN5 inhibitor with an IC50 of 0.36 μM. CSN5-IN-2 can increase the level of Cullin 1 neddylation, and downregulate the expression of RAD51 and PD-L1 in cancer cells. CSN5-IN-2 has anti-tumor activity, and its effect is better when combined with Talazoparib (HY-16106) .
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