2 Results for "

CanAg-positive

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "CanAg-positive" in MCE Product Catalog:

1
1 Cited Publications
Referencia número: HY-P99493
No. CAS: 868747-45-9
Synonyms: IMGN242; huC242-DM4

Áreas de investigación:  

Cancer

Cantuzumab ravtansine (IMGN242; huC242-DM4), an ADC, is a humanized monoclonal antibody, huC242, covalently linked via a disulfide bond to DM4 (HY-12454). Cantuzumab ravtansine has broad antitumor efficacy against a range of CanAg-positive human tumor xenografts .
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Referencia número: HY-P99492
No. CAS: 400010-39-1
Synonyms: SB-408075; huC242-DM1

Áreas de investigación:  

Cancer

Cantuzumab mertansine (SB-408075; huC242-DM1), an ADC, is an immunoconjugate of the potent maytansine derivative (DM1 (HY-19792)) and the humanized monoclonal antibody (huC242) directed to CanAg. Cantuzumab mertansine has cytotoxic toward colon cancer cells and has broad antitumor efficacy against a range of CanAg-positive human tumor xenografts .
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