2 Results for "

Ciglitazone

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Ciglitazone" in MCE Product Catalog:

1
1 Cited Publications
Cat. No.: HY-W011220
CAS No.: 74772-77-3
Synonyms: ADD-3878; U-63287
Target:  

PPAR

Research Areas:  

Cardiovascular Disease Cancer

Ciglitazone is a potent and selective PPARγ agonist (EC50=3 μM). Ciglitazone inhibits proliferation and differentiation of th17 cells. Ciglitazone is a hypoglycemic agent orally active in the obese-hyperglycemic animal models. Ciglitazone induces apoptosis accompanied by activation of p38 MAPK and nuclear translocation of apoptosis inducing factor (AIF) in opossum kidney (OK) renal epithelial cells .
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Cat. No.: HY-121058
CAS No.: 87858-57-9
Synonyms: ADD 4743
Research Areas:  

Metabolic Disease

AD 4743 (ADD 4743) is a metabolite of Ciglitazone (HY-W011220). AD 4743 is an adipogenic agent. AD 4743 induces FPRP accumulation and accumulation of lipid droplets. AD 4743 inhibits cell proliferation of preadipose cells .
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