2 Results for "

Complement C1s-IN-1

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "Complement C1s-IN-1" in MCE Product Catalog:

Cat. No.: HY-149278
CAS No.: 3033831-40-9
Target:  

Complement System

Research Areas:  

Inflammation/Immunology

Complement C1s-IN-1 is a potent, selective, orally active and cross the blood-brain barrier C1s inhibitor with an IC50 value of 36 nM .
loading...
    loading...
Cat. No.: HY-P10827
CAS No.: 1356469-36-7
Target:  

Complement System

Research Areas:  

Inflammation/Immunology

PIC1 PA, a 15 amino-acid peptide, is a potent PIC1 analog that inhibits classical pathway mediated complement activation. PIC1 PA functionally disrupts the C1s-C1r-C1r-C1s/MASPs interaction with collagen-like region (CLR) of C1q/MBL, respectively. PIC1 PA specifically binds to the CLR of C1q and bounds to purified C1q with a mean equilibrium dissociation constant (KD) of 33.3 nM .
loading...
    loading...